Polyetheretherketone (PEEK) is a high-strength, chemically inert and temperature-stable high-performance polymer. It is the most commonly used polymer material in orthopedics and favored in spinal surgery, due to its physical properties and similarity to human cortical bone.
However, compared to titanium implant surfaces, poor cell adhesion is a major problem with PEEK implant surfaces. To solve this problem, we are developing coatings for PEEK implant surfaces that can significantly improve the ingrowth behavior of PEEK-based implants. In addition, the coating should have antibacterial properties and reduce the initial adsorption of non-specific proteins during implantation. Therefore, it is necessary to modify the PEEK surface to increase the cell adhesion and to achieve an improved osseointegration of the PEEK coating. Coatings of modified biopolymers can be suitable for this purpose, as they can simulate the biochemical environment of an extracellular matrix (ECM).
Furthermore, derivatized oligoesters are available which, in an appropriate composition, improve the interface properties between the implant and the bone tissue. With regard to synthesis and coating, various promising strategies have being pursued to provide PEEK surfaces with adhesion-improving, protein-repellent and antibacterial properties.
Dr. Albrecht Berg
Phone: +49 3641 282555